A dark force threatens Ponyville, and the Mane 6 - Twilight Sparkle, Applejack, Rainbow Dash, Pinkie Pie, Fluttershy, and Rarity - embark on an unforgettable journey beyond Equestria where they meet new friends and exciting challenges on a quest to use the magic of friendship to save their home.

Every four years, Canterlot High has 'The Friendship Games' where they must rival with different schools with a series of different sporting events and every year, the cup has gone to Crystal Prep. So Fluttershy, Pinkie Pie, Rainbow Dash, Rarity, Applejack, and Sunset Shimmer must work together to win the cup. But they find out that the other Twilight Sparkle is on the opposing team.

Music rules and rainbows rock as Twilight Sparkle and pals complete for the top spot in the Canterlot High "Mane Event" talent show. The girls must rock their way to the top, and outshine rival Adagio Dazzle and her band The Dazzlings, to restore harmony back to Canterlot High.

In Equestria, the newly crowned Princess Twilight Sparkle is still trying to adjust to her new status and wings. However, Sunset Shimmer a renegade former student of Princess Celestia, steals her magic crown and escapes to another world. Twilight is charged with recovering the crown and she and her companion, Spike, pursue the thief. Crossing over, Twilight finds that she has been changed into a powerless human in a high school world populated with teenage human counterparts of her friends. To...